Controlling the where, when and how long of vaccine delivery with Darrell Irvine, PhD
Scientists are designing vaccines that produce stronger, more durable immune responses. In this free Front Row lecture, Scripps Research Professor and the Lita Annenberg Hazen Chair Darrell Irvine will explore how controlling where vaccine components travel in the body—and when and for how long they are delivered—could improve vaccine performance. Irvine will highlight two approaches his lab has advanced into clinical testing: saponin/monophosphoryl lipid A nanoparticles (SMNP), a new vaccine adjuvant designed to strengthen immune responses, and “escalating dose immunization,” a dosing strategy that delivers a vaccine gradually over time. Together, these technologies offer new ways to guide vaccine components to lymphoid tissues, where immune responses take shape.
About Scripps Research
Committed to unraveling the intricacies of the human body and translating our discoveries into tangible global impact, Scripps Research is consistently ranked among the most influential non-profit research institutes in the world . Throughout our 100-year history, our scientists have expanded the boundaries of scientific understanding and played a pivotal role in the development of 18 FDA-approved medicines that have impacted the lives of countless individuals worldwide .
The Front Row lecture series, now in its ninth season, offers an exclusive glimpse into groundbreaking scientific discoveries in action. Many of these breakthroughs are the result of years of tireless work—made possible by the support of our community.
As we enter another century of science changing life at Scripps Research, our focus remains the same: fueling world-class fundamental and translational research to accelerate the development of medical advances for the benefit of human health .